Why NAD+ Is Leading the Longevity Conversation Right Now

NAD+ continues to be one of the most talked-about molecules in longevity and cellular health, but clear guidance on what actually works hasn’t always kept pace.

NAD+ has quickly become one of the most visible categories in the wellness and longevity space. But as adoption grows, meaningful innovation hasn’t always kept pace, leaving practitioners and patients navigating a crowded field with surprisingly little progress in how NAD+ support is actually advanced.

This matters for practitioners.

Why NAD+ Matters

NAD+ plays a central role in cellular energy, repair, and resilience. As levels naturally decline with age, the body’s ability to adapt, recover, and function efficiently begins to slow.

NAD+ is involved in several key hallmarks of aging, including:

Mitochondrial function — supports cellular energy production
Inflammatory balance — helps manage oxidative stress
Stem cell vitality — supports cellular renewal capacity
Epigenetic stability — supports healthy cellular signaling

The challenge isn’t understanding NAD+ — it’s restoring levels inside the cell, where impact occurs.

The Limitations of Traditional NAD+ Options

While demand for NAD+ is growing, many delivery methods fall short in practice:

Oral NAD+
Unstable with low bioavailability.

Precursors (NR, NMN, Niacin)
Require conversion, produce variable results, and may cause side effects.

IV therapy
Costly, time-intensive, and difficult to scale for most patients.

Adding to the concern, independent testing has shown that many NAD+ supplements fail to meet label claims, making product quality a critical factor.

Why NADEssence™ Is Different

NADEssence™ was developed to address the core issue: delivering NAD+ in a form that is stable, measurable, and clinically validated.

✔ Demonstrated 52% average increase in intracellular NAD+
✔ Randomized, double-blind, placebo-controlled human trial
✔ Patented technology supporting stability through digestion and absorption
✔ Oral delivery with minimal to no reported side effects
✔ Consistently meets label claims

This makes NADEssence™ a practical option for real-world clinical use.

The Science Behind the Formula

Developed over 12 years, NADEssence™ was studied using an extensive clinical model:

5,000+ data points per participant
100% of treatment participants showed increased intracellular NAD+
85+ biomarkers favorably impacted
65+ biological pathways positively influenced
Proven 2-year shelf stability

The result: reliable NAD+ support without IVs or guesswork.

Key Areas of Support

Metabolic Health
Supports glucose and lipid metabolism and healthy weight management strategies.

Cognitive & Neuromuscular Function
Supports brain health, mental clarity, and neuromuscular communication.

Inflammatory Balance
Supports healthy inflammatory response and skin health.

Dosing Overview

Dry Powder
Mix 1 level scoop (~1 g) in 4 oz water. Swish 45–60 seconds per sip before swallowing. Consume within 24 hours.

Loading Phase

500 mg twice daily for 5–14 days
Optional addition of one 100 mg sublingual tablet daily

Maintenance Phase

Powder: typically every 4–5 days as directed

Sublingual: one 100 mg tablet daily
(May require ~90 days to reach saturation)

Why It Matters for Your Practice

NADEssence™ offers practitioners a clinically validated, oral NAD+ solution that’s accessible, scalable, and easy for patients to stay consistent with.

No IVs.
No complexity.
Just clear, cellular-level support.

Add NADEssence™ to your protocols and start recommending with confidence.

NADEssence™: NAD+ Supplementation You Can Trust